AmChams in Europe (ACE), established in 1963 as the European Council of American Chambers of Commerce, serves as the umbrella organization for 49 AmChams across Europe and Eurasia. It works to promote the importance of the transatlantic economy, representing independent, non-governmental business organizations accredited by the U.S. Chamber of Commerce, and operates in 47 countries as the largest network of international chambers of commerce.

The transatlantic economy is valued at approximately $9.8 trillion in 2025, reflecting deep economic integration between the United States and Europe. This relationship includes around $2.3 trillion in trade in goods and services and $7.5 trillion in foreign affiliate sales, highlighting the scale of mutual business activity. In goods trade, U.S. exports to Europe are estimated at $617 billion, while European exports to the U.S. reach $840 billion. In services, U.S. exports to Europe amount to $489 billion, compared to $350 billion in European exports to the U.S. Investment ties are equally significant, with Europe accounting for 56% of U.S. foreign direct investment (FDI) worldwide and representing 56% of global FDI in the U.S. by ultimate beneficial ownership. These economic links support approximately 16 million jobs across both regions, including 5.3 million employees of European companies in the U.S. and 4.6 million employees of U.S. companies in Europe.